Hill v = V·Sⁿ/(Kⁿ+Sⁿ): n is the log-log slope at S = K

Hill cooperativity (A. V. Hill 1910). Multi-site substrate binding where n > 1 indicates positive cooperativity (one binding event raises affinity for the next), n = 1 Michaelis-Menten, n < 1 negative cooperativity. Classical example:…