H3K4me3

Layer 3 — Biologyin the Epigenetics And Chromatin subtree

Trimethylation of H3 Lys4 — active-promoter mark. Written by SET1/MLL; bound by TAF3/CHD1 (PHD, chromo). Rare at repressed genes; bivalent H3K4me3/H3K27me3 at poised developmental genes.

Related concepts

Histone post-translational modification

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