Histone post-translational modification

Layer 3 — Biologyin the Epigenetics And Chromatin subtree

Covalent tags on histone tails (H3/H4 Lys/Arg/Ser): acetylation, methylation, phosphorylation, ubiquitination, SUMOylation. Form a 'histone code' read by effectors (bromo/chromo/PHD domains).

Related concepts

Epigenetics
H3K4me3
H3K27me3
Histone acetylation
ChIP-seq
Chromatin remodeller

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