Chemical starting point with demonstrated biological activity on the target (IC₅₀ typically 100 nM–10 μM) that is iteratively optimised for potency, selectivity, ADMET, and IP. Sourced from HTS, fragment-based design, natural products, or…
Chemical starting point with demonstrated biological activity on the target (IC₅₀ typically 100 nM–10 μM) that is iteratively optimised for potency, selectivity, ADMET, and IP. Sourced from HTS, fragment-based design, natural products, or…