Michaelis-Menten v = V·S/(Km+S): steady-state ES kinetics

Layer 2 — Chemistryin the bioorganic-chemistry subtree

Michaelis-Menten saturation kinetics (Michaelis & Menten 1913; Briggs-Haldane 1925 steady-state generalisation). For the single-substrate reaction E + S ⇌_{k₁,k₋₁} ES →_{kcat} E + P, steady-state d[ES]/dt = 0 gives [ES] = [E]_tot·S/(K_m +…

Related concepts

Catalysis
Chemical equilibrium
v = V·S/(Km+S) at S = Km ⇒ v = V/2 (half-saturation anchor)
1/v = Km/(V·S) + 1/V; y-intercept 1/V, x-intercept −1/Km

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