Removal of introns and ligation of exons by the spliceosome (U1/U2/U4/U5/U6 snRNPs + proteins, ~200 components). Two-step transesterification via 2′-OH branch-point attack + exon ligation.
Removal of introns and ligation of exons by the spliceosome (U1/U2/U4/U5/U6 snRNPs + proteins, ~200 components). Two-step transesterification via 2′-OH branch-point attack + exon ligation.