Nowak-May target-cell-limited ODE: dT/dt = λ - dT - βTV; dI/dt = βTV - δI; dV/dt = pI - cV. Yields R_0 = βλp/(dδc); in HIV/HBV/HCV the model fit to viral-load decay extracts δ, c, p and guides drug-efficacy estimation (Perelson 1996).
Nowak-May target-cell-limited ODE: dT/dt = λ - dT - βTV; dI/dt = βTV - δI; dV/dt = pI - cV. Yields R_0 = βλp/(dδc); in HIV/HBV/HCV the model fit to viral-load decay extracts δ, c, p and guides drug-efficacy estimation (Perelson 1996).