β-cell-secreted 51-aa peptide hormone binding insulin receptor (RTK). Promotes glucose uptake (GLUT4 translocation), glycogen synthesis, lipogenesis. Deficiency/resistance → diabetes mellitus.
β-cell-secreted 51-aa peptide hormone binding insulin receptor (RTK). Promotes glucose uptake (GLUT4 translocation), glycogen synthesis, lipogenesis. Deficiency/resistance → diabetes mellitus.