CDKN2A-encoded cyclin-dependent-kinase inhibitor p16-INK4a accumulates with age in nearly every mammalian tissue — among the most reproducible molecular biomarkers of biological age. Functions as both cause and marker: p16 is upregulated…
CDKN2A-encoded cyclin-dependent-kinase inhibitor p16-INK4a accumulates with age in nearly every mammalian tissue — among the most reproducible molecular biomarkers of biological age. Functions as both cause and marker: p16 is upregulated…